The 91-ranked Indian ace was well and truly beaten 4-6, 6-7 (3-7) by 95-ranked Kazakhstan's Galina Voskoboeva in Paris on Tuesday.
Divij Sharan and Samantha Murray Sharan paired on the mixed doubles court for the first time and defeated Ariel Behar and Galina Voskoboeva 6-3, 5-7, 6-4 in the first round on Friday.
Leander Paes kept the Indian challenge alive in the mixed doubles event of the French Open by moving to the second round along with partner Jelena Jankovic.
Serena Williams took another emphatic step in defense of her U.S. Open title by crushing Galina Voskoboeva of Kazakhstan 6-3, 6-0 on Thursday to reach the third round of the year's final Grand Slam.
Sania Mirza and Anastasia Rodionova breezed past Megan Moulton-Levy and Lindsay Lee-Waters in straight sets to book a semi-final berth in the Estoril Open.
The seventh seeded Indian pair beat Galina Voskoboeva of Kazakhstan and Italy's Daniele Bracciali 6-4, 6-2 in the semi-finals on Wednesday. They will meet Poland's Klaudia Jans-Ignacik and Santiago Gonzalez of Mexico, who got the better of the fifth seeds, India's Leander Paes-Elena Vesnina of Russia 7-6 (7-2), 6-3 in the second semi-final.
France's Marion Bartoli and Russia's Svetlana Kuznetsova suffered shock first-round exits from the Rogers Cup as the two seeded players were eliminated on Monday by a pair of gritty qualifiers.
World number one Amelie Mauresmo lost 6-4, 7-5 to defending champion Lindsay Davenport in the New Haven quarter-finals.
The Indian pair first stunned the second seeded US-Swedish pair of Lisa Raymond and Simon Aspelin 6-3, 2-6, 10-7 in the second round to enter the quarter-finals, and then advanced a round further thanks to a walkover from their quarter-final opponents, seventh seeds Kveta Peschke and Martin Damm, who had beaten Galina Voskoboeva and Frantisek Cermak 6-1, 6-1 in their second round match.
Shikha and Neha Uberoi were knocked out of the doubles competition at the WTA Bell Challenge.
Shikha and Neha beat the Russian duo of Galina Voskoboeva and Anastassia Rodionova in the first round of the $175,000 Bell Challenge.
India's Shikha Uberoi bowed out of the Sunfeast Kolkata Open, losing to Hana Sromova in another first round match.
The Indian ace beat Ukraine's Kateryna Bondarenko in straight sets to advance to the main draw of the Acura Classic.
The India ace will meet the Ukraine lass in final qualifying round of the Acura Classic tennis tournament in San Diego.
Clay has never been Sania Mirza's favourite surface but the Indian blamed lack of match practice due to injury for her first round exit from the French Open.